Peter Griffin is technically the main protagonist of the popular cartoon series known as Family Guy, however he is not as nice a character as some may imagine - in fact throughout the course of the series Peter has caused much misery for those around himself: often this is due to stupidity but there have been times when Peter has deliberately caused harm or misfortune on others.
Peter Griffin is not alone in this respect as he is shown to have an "evil" brother known as Thaddeus Griffin, suggesting antagonism runs in his family, that explains about his son, Stewie Griffin (though in fairness Peter does have some moments of being a caring individual, though they are rare).
- Probably his most villainous acts was his attempt to get a promotion at work by blowing up a billboard advertising a rival brewery. Unfortunately, he had placed the explosives in the wrong building, which just so happened to be a children's hospital. When Peter had his boss, Angela, look out the window to watch the billboard explode, he had caused the destruction of the hospital instead. By the end of the episode, when Peter had passed Third Grade and was eligible for a promotion (so he can use the Executive Bathroom), Angela refused to give it to him. Her reason was that nobody had forgotten the burning of the children's hospital, which had resulted in fourteen deaths. The FBI had eventually learned that it was Peter, and he was sentenced to seven days in prison.
- Peter also pretended that his son; Chris Griffin was dying so he could save a canceled TV show
- Peter also made Chris lose his girlfriend, by giving him bad advice on how to date a girl, and how to act around her.
- Peter constantly abuses Meg, whether talking down to her, farting in her face, almost drowned, and in a cutscene, Peter shot Meg. He even went to Meg's school to create a false story that Luke Perry was gay and burned Meg's story about Mayor Adam West.